ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2014, Vol. 45 ›› Issue (1): 101-106.doi: 10.11843/j.issn.0366-6964.2014.01.014

Previous Articles     Next Articles

Comparison of the Susceptibility of Three Different Local Chicken Lines in China to Very Virulent Strain rMd5

CUI Ning, SU Shuai, CHEN Zi-meng, ZHAO Xiao-min, CUI Zhi-zhong*   

  1. (Animal Science and Technology College, Shandong Agricultural University, Taian 271018, China)
  • Received:2013-07-23 Online:2014-01-23 Published:2014-01-23

Abstract:

This experiment was conducted to study the pathogenicity of very virulent MDV strain rMd5 between three different local chicken lines (Ji-ning-bai-ri, Wen-shang-lu-hua, Shou-guang-hei) in China. rMd5 strain was inoculated to chickens by intraperitoneal injection, 1-day-old chicken with 500 PFU and 7-day-old chicken with 1 500 PFU. The feeding trial lasted for 90 days. rMd5 causes specific lesions of Mareks disease in three different local chicken lines, but the degree of the pathogenicity differs significantly: the mortality and oncogenicity of Shou-guang-hei are significantly higher than the other two chicken lines, which is almost similar to SPF chicken. In addition, the transmission capacity of rMd5 in Shou-guang-hei is the highest; By contrast, the resistance of Ji-ning-bai-ri and Wen-shang-lu-hua lines to rMd5 infection and disease are greater. Therefore, Ji-ning-bai-ri and Wen-shang-lu-hua can be candidate lines to screen for genetic resistance genes and study genetic resistance mechanism.

CLC Number: